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A Chemists’ Guide to Skincare That Works

Stem cells and snail slime are not on the list

Dana G Smith
Elemental
Published in
8 min readApr 10, 2019

Credit: Makidotvn/iStock/Getty Images Plus

TThe amount of skin care options available to slather on your face is dizzying. There are lotions, serums, masks, oils, and acids as well as stem cells, snail slime, charcoal, and even diamonds. And with complicated ingredient lists, it can feel like you need a chemistry degree to purchase a basic moisturizer.

Navigating the $134.8 billion global skin care industry is made even more confusing because many dermatologists have skin in the game. They might be paid consultants for cosmetic companies, sell high-end nonprescription products at their private practices, or even have their own skin care lines they want to promote.

“If these products work so well, number one: You wouldn’t see dermatologists aging, and you do,” says New York-based dermatologist Dr. Fayne Frey, author of FryFace, a website aimed at demystifying skin care. “Number two: You wouldn’t see all my cosmetic dermatology friends offering laser treatments and peels,” she continues, because if the products worked well, doctors wouldn’t have to rely on more complex treatments.

So what do impartial cosmetic chemists and dermatologists like Frey recommend? And what’s overpriced junk that will just fill up your pores while emptying your wallet? Read on.

Retinoids

The three basic tenets of skin care remain the same: Wash your face, use sunscreen during the day, and apply a moisturizer at night. But if you’re looking to go beyond the basics, it helps to have a little insider knowledge about the industry. Every skin care product you can buy online or at a drugstore is technically a cosmetic, meaning it could potentially change the appearance of your skin, but it cannot, by definition, change the skin cells themselves. Only drugs approved by the Food and Drug Administration (FDA) are allowed to alter the structure or function of your skin.

“Anything that’s regulated as a drug is going to have the most evidence behind it,” says Michelle Wong, a PhD chemist and science educator who moonlights as the beauty blogger Lab Muffin. (Wong is not affiliated with any brands, although she does occasionally receive free product samples and writes sponsored posts. She takes special…

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Elemental
Elemental

Published in Elemental

Elemental is a former publication from Medium for science-backed health and wellness coverage. Currently inactive and not taking submissions.

Dana G Smith
Dana G Smith

Written by Dana G Smith

Health and science writer • PhD in 🧠 • Words in Scientific American, STAT, The Atlantic, The Guardian • Award-winning Covid-19 coverage for Elemental

Responses (33)

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Thanks for sharing the article! Dana G Smith — your writing is delightful! :) This article is an eye opener for anyone who is in wondering if they need a bigger bathroom or a new shelf to fit all the products!
Skin care is very much top of mind for…

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One popular ingredient is niacinamide, a form of vitamin B3. Like retinoids, niacinamide appears to increase cell turnover on the top layer of the skin and can reduce dark spots

Niacinamide does not increase cell turnover, however, it does improve hyperpigmentation by inhibiting tyrosinase the enzyme responsible for pigment. Niacinamide also slows down melanosome transfer to surrounding skin cells thus reducing visible patches of pigment.

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I spent over 12 years in the cosmetic industry working with all the big guys. It’s a bunch of BS, there is little to no science, and Marketing rarely pays heed to the limitations of the products except when a claims lawyer tells them they need it…

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