The Nuance
Could the ‘Spirit Molecule’ Cure Your Depression?
DMT — a psychedelic linked to near-death experiences — is the focus of new depression research
In December of 1990, a psychiatrist named Rick Strassman injected two men with N,N-Dimethyltryptamine, a potent hallucinogenic compound better known as DMT.
“I died and went to heaven,” one of the men recounted to Strassman after the drug had worn off. “It was a cosmic blowtorch, a tempest of color.”
At that time, Strassman, was an associate professor at the University of New Mexico. (He still is.) His pioneering work on DMT helped revive the scientific community’s interest in the therapeutic potential of psychedelic compounds, which some experts are now calling “the most promising treatment approaches in contemporary psychiatry.”
But while DMT, which some call “the spirit molecule,” helped catalyze our current moment’s enthusiasm for psychedelics, some other drug compounds — namely psilocybin (magic mushrooms), ketamine, and MDMA — have hogged most of the spotlight and research dollars.
That may be changing. I recently wrote a feature about DMT for Vice. I learned that psychedelic researchers at both Johns Hopkins and Ohio State University have lately looked…
