What the Data on Coronavirus Omicron Actually Shows

A lot of speculation about the new variant is not super helpful

F. Perry Wilson, MD MSCE
Elemental
Published in
6 min readNov 29, 2021

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Thirty thousand nucleotide bases.

Just 30,000 letters of the alphabet of life are enough to create the entire SARS-CoV-2 virus, provided those letters find the machinery present in all of our cells to do the hard work. Those letters get copied, and copied, and copied with each new infection, in each new cell, and errors compound. The vast majority of those errors make SARS-CoV-2 a less effective virus. But some have the opposite effect, honing the virus to accomplish the only thing that RNA really wants to do — make more copies of itself. This is evolution. And this is how variants are born.

A new variant takes center stage this week — notable primarily for the dramatic international response to its emergence. Countries around the world are slamming their borders shut. What makes omicron so special?

There have been a flurry of stories and rather breathless news reporting on the new variant, and I appreciate that the situation is evolving rapidly, but for now, I wanted to take an opportunity to try to put all the hard facts in one place.

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F. Perry Wilson, MD MSCE
Elemental

Medicine, science, statistics. Associate Professor of Medicine and Public Health at Yale. New book “How Medicine Works and When it Doesn’t” available now.