Ketamine Is Revealing a New Understanding of Depression and the Brain
Some experts view ketamine as a tool to unravel the biological causes of depression and, perhaps someday, cure it
If you or someone you know need help, consider calling the National Suicide Prevention Lifeline at 1–800–273-TALK (8255) for English, 1–888–628–9454 for Spanish.
“Some people say ketamine makes them feel like a marshmallow.”
That’s how the ketamine clinic’s therapist explained it to me through my computer screen during our initial meeting. I’d already asked several people what ketamine would feel like, and each time I got a slightly different answer. But the overall consensus was that I’d feel floaty, that I might see things, and that I might feel relaxed or unnerved. My greatest fear was having a panic attack during the experience. “We can always give you something for that,” the therapist assured me.
My recent path to ketamine treatment was at least 20 years in the making. I could no longer remember what it felt like not to be depressed, and not reflexively jump to the worst possible outcome of any scenario. I could not remember what it felt like to want to exist. The isolation and tragedy of the pandemic — saying goodbye to my unconscious grandmother over a…
