Plasma From Coronavirus Survivors Could Treat Current Patients

A 100-year approach shows promise for Covid-19

Emily Mullin
Elemental

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A doctor who has recovered from Covid-19 donates plasma in Wuhan, China. Photo: STR/Getty Images

InIn 1890, Emil von Behring and Shibasaburo Kitasato published a landmark study showing that they could cure guinea pigs infected with diphtheria. To do it, the scientists injected the guinea pigs with serum taken from animals that were immune to the disease. At the time, diphtheria was a leading cause of death among children.

Behring and Kitasato immediately realized its application for human diseases and called it “serum therapy.” The discovery led to the first successful diphtheria treatment and, eventually, a vaccine. Doctors later used it during the 1918 Spanish flu pandemic, and in many cases, it helped patients recover. Now, the idea is being revived to treat people who are newly infected with the novel coronavirus.

Serum, or plasma, is the clear, yellowish liquid component of the blood. Scientists think it could be an effective treatment for patients hospitalized with Covid-19 or those exposed to the virus who are at high risk of getting sick, like health care workers and people with weak immune systems.

Plasma from recovered patients, also known as convalescent plasma, bolsters the immune system against other pathogens because it contains powerful antibodies. “When people get…

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Emily Mullin
Elemental

Former staff writer at Medium, where I covered biotech, genetics, and Covid-19 for OneZero, Future Human, Elemental, and the Coronavirus Blog.