What’s the Best Way to Use Ketamine for Depression?

Doctors say a nasal spray may not be the best way to administer a promising new depression drug

Illustration by George Wylesol

“When you give ketamine by nasal spray there are several factors that you don’t control.”

Hovering over all of this is a larger question: While esketamine is widely being heralded as an innovative and potentially lifesaving treatment, some researchers and medical professionals argue that the FDA’s approval of the drug was hasty, and question whether the nasal spray is the best way to use the drug. While an IV infusion can accurately deliver a measured dose, some evidence suggests this might not be the case with a nasal spray.

writer. www.tessalove.com @tessamlove

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