No Two Brains Are the Same: How Neuroscience Is Advancing to Account for This

A researcher explains the significance of brain organoids

Gabriel A. Silva
Elemental

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A human-derived brain organoid. Image courtesy of Alysson Muotri’s lab at the University of California, San Diego

Your brain is not like mine. In fact, your brain is not like anyone else’s. I don’t mean that in some philosophical or abstract way; I mean it literally. The precise wiring of your brain is unique to you. During development, your genes specified a blueprint that resulted in your brain having roughly the same organization as mine. But that genetic blueprint wasn’t designed to specify the precise connection patterns between all the neurons in your brain.

The exact wiring diagram of the networks of cells in your brain is the result of random processes influenced by external and environmental factors and stressors — in other words, the ways in which you interact with the world and the world interacts with you. As a result, how your brain takes in and processes information is also specific to you. You truly are a neurobiologically unique individual. We all are.

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Gabriel A. Silva
Elemental

Professor of Bioengineering and Neurosciences, University of California San Diego