Illustration: Kieran Blakey

The Nuance

Activating the Vagus Nerve Might Lower Your Covid-19 Risk

While physical distancing and masks are crucial, social interaction could calm the immune system and turn down inflammation

Markham Heid
Elemental
Published in
5 min readNov 25, 2020

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Like other apes, humans are social animals. We evolved to live in codependent communities, and we do poorly if deprived of interpersonal contact.

Everyone has a different threshold for social interaction. But nearly all of us tend to become distressed when cut off from others, and our immune system responds to this distress by ramping up its defenses. A new study in the journal Neuroscience & Biobehavioral Reviews finds that social isolation is associated with a rise in inflammation-promoting molecules, including some that are implicated in severe Covid-19. And past research has linked loneliness to poor cellular immune health and increased viral loads during an infection.

All of these cellular and immune changes are worrying in the context of SARS-CoV-2. Inflammation is a unifying feature

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Markham Heid
Elemental

I’m a frequent contributor at TIME, the New York Times, and other media orgs. I write mostly about health and science. I like long walks and the Grateful Dead.